Cannabidiol (CBD), extracted from the hemp plant, is often marketed as a potential painkiller, particularly for conditions like osteoarthritis of the knee. While animal studies have indicated its anti-inflammatory and pain-relieving properties, a recent clinical study led by pain researchers at MedUni Vienna reveals that CBD, even in high doses, does not exhibit significant pain-relieving effects in humans.
The study, involving 86 participants suffering from severe knee joint pain due to osteoarthritis, was conducted over eight weeks and published in The Lancet Regional Health – Europe.
The participants, averaging around 63 years of age, were divided into two groups – one receiving high-dose CBD orally, and the other a placebo. The study, meticulously controlled, demonstrated that CBD did not provide more significant pain relief than the placebo. This conclusion challenges the perception that CBD could serve as an alternative pain therapy for knee osteoarthritis.
What The Study Means
The study emphasizes the need for continued exploration of effective options for managing knee pain associated with osteoarthritis. Currently, conventional analgesics such as diclofenac, ibuprofen, and tramadol are utilized, presenting challenges due to potential side effects and contraindications, especially in elderly patients.
Despite CBD showing analgesic effects in animal studies, this clinical research underscores the necessity for high-dose oral medication to establish CBD’s efficacy, highlighting the skepticism surrounding CBD-containing painkillers for topical applications. The study’s focus on chronic knee pain provides valuable insights into the limited analgesic potential of CBD in this common condition.
It’s worth noting that CBD is a natural substance readily available for sale in the EU. While it lacks intoxicating effects and is not classified as a narcotic, liver toxicity remains a known side effect. In the realm of medicine, CBD has been extensively researched and approved under pharmaceutical law for treating certain types of childhood epilepsy, such as Dravet syndrome and Lennox-Gastaut syndrome. However, the study indicates that knee osteoarthritis pain may not be effectively addressed through CBD, leaving room for future research to explore its potential applications in other medical contexts.
Do you use CBD to manage joint pain? How does it work? Leave your experience in the comments below.